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“alex avdeef”

Showing 1 - 12 of 12 results for “alex avdeef”
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  • Predicting Solubility of New Drugs

    Handbook of Critically Curated Data for Pharmaceutical Research

    by Alex Avdeef ...
    In pharmaceutical research, solubility plays a key part in the assessment of pharmacokinetic risks. Poor drug absorption, reduced efficacy, excessive metabolism, and adverse reactions are frequently related to issues of drug solubility. During early discovery research at pharmaceutical companies, many thousands of molecules are considered. Most are rejected due to perceived unfavorable properties. ... Read more

    $385.00 USD

  • Absorption and Drug Development

    Solubility, Permeability, and Charge State

    by Alex Avdeef ...
    Explains how to perform and analyze the results of the latest physicochemical methodsWith this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to ... Read more

    $152.00 USD

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  • Pharmaceutical Lifecycle Management

    Making the Most of Each and Every Brand

    by Tony Ellery, Neal Hansen ...
    A comprehensive guide to optimizing the lifecycle management of pharmaceutical brandsThe mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the lifecycle management (LCM) of brand drugs essential for pharmaceutical companies looking to maximize the value of their products. Demonstrating how different measures can be combined to create ... Read more

    $88.00 USD

  • Principles and Practice of Clinical Research

    Edited by Frederick P Ognibene, John I. Gallin ...
    The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory ... Read more

    $112.49 USD

  • Early Drug Development

    Strategies and Routes to First-in-Human Trials

    Edited by Mitchell N. Cayen ...
    The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an Investigational New Drug (IND) application. By explaining the nuts and bolts of preclinical development activities and their ... Read more

    $161.00 USD

  • Pharmacology Volume 3

    Includes Respiratory System, The Human Cardiovascular, Lymphatic, Urogenital Systems, Cardiac, Vasodilator Drugs, Hematopoietic System, Antihypertensive, Diuretic, Anti-diuretic Agents, Toxicology, and Poison Control

    Edited by IML Training ...
    Series series Pharmacology
    Pharmacology Volume 3 of 5Drugs that act upon the respiratory system, cardiovascular system, or urinary system are frequently dispensed in pharmacies. This is because conditions that affect these systems (that is, hypertension affecting the cardiovascular system) affect many people. Consequently, it is imperative that you have an understanding of these systems and the drugs that act on them.As ... Read more

    $5.99 USD

  • Practical Biostatistics

    A Friendly Step-by-Step Approach for Evidence-based Medicine

    by Mendel Suchmacher, Mauro Geller ...
    Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical ... Read more

    $62.09 USD

  • Anticancer Genes

    Edited by Stefan Grimm ...
    Series series Biomedical and Life Sciences (R0)
    This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as “Anticancer Genes”, are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application.Anticancer Genes provides an overview of this nascent field, its genesis, ... Read more

    $89.09 USD

  • Systemic Vasculitides: Current Status and Perspectives

    Edited by Franco Dammacco, Domenico Ribatti, Angelo Vacca ...
    Series series Biomedical and Life Sciences (R0)
    In spite of their relatively low prevalence, systemic vasculitides have been the object of intensive basic and clinical investigations over the last few years. As a consequence, important advancements have been achieved: from updated diagnostic and classification criteria and a more rational nomenclature to the recognition of an expanding spectrum of clinical manifestations and potentially ... Read more

    $98.09 USD

  • Jungle Laboratories

    Mexican Peasants, National Projects, and the Making of the Pill

    by Gabriela Soto Laveaga ...
    In the 1940s chemists discovered that barbasco, a wild yam indigenous to Mexico, could be used to mass-produce synthetic steroid hormones. Barbasco spurred the development of new drugs, including cortisone and the first viable oral contraceptives, and positioned Mexico as a major player in the global pharmaceutical industry. Yet few people today are aware of Mexico’s role in achieving these ... Read more

    $21.59 USD

  • Understanding the Neurotransmitters: Key to the Workings of the Brain

    by Walter Birkmayer, Peter Riederer ...
    Translated by Karl Blau ...
    Series series Medicine (R0)

    $89.09 USD

  • Delivery Strategies for Antisense Oligonucleotide Therapeutics

    Edited by Saghir Akhtar ...
    Series series CRC Press Revivals
    With contributions from leading experts, this book is the first to focus solely on addressing the problems and reviewing the strategies currently being used to improve the delivery of antisense nucleic acids. Important delivery issues, such as improving biological stability, improving cell-specific targeting and cellular uptake, manipulating subcellular distribution and producing liposomal ... Read more

    $86.99 USD