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  • Tidy Modeling with R

    A Framework for Modeling in the Tidyverse

    Get going with tidymodels, a collection of R packages for modeling and machine learning. Whether you're just starting out or have years of experience with modeling, this practical introduction shows data analysts, business analysts, and data scientists how the tidymodels framework offers a consistent, flexible approach for your work.RStudio engineers Max Kuhn and Julia Silge demonstrate ways to ... Read more

    $41.99 USD

  • Nonclinical Statistics for Pharmaceutical and Biotechnology Industries

    Series series Mathematics and Statistics (R0)
    This book serves as a reference text for regulatory, industry and academic statisticians and also a handy manual for entry level Statisticians. Additionally it aims to stimulate academic interest in the field of Nonclinical Statistics and promote this as an important discipline in its own right. This text brings together for the first time in a single volume a comprehensive survey of methods ... Read more

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  • Fundamentals of Clinical Trials

    Series series Mathematics and Statistics (R0)
    This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two ... Read more

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  • Statistics Explained

    An Introductory Guide for Life Scientists

    An understanding of statistics and experimental design is essential for life science studies, but many students lack a mathematical background and some even dread taking an introductory statistics course. Using a refreshingly clear and encouraging reader-friendly approach, this book helps students understand how to choose, carry out, interpret and report the results of complex statistical analyses ... Read more

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  • Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models

    This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects• Provides examples of nonlinear modeling ... Read more

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  • Applied Longitudinal Analysis

    Series Book 998 - Wiley Series in Probability and Statistics
    Praise for the First Edition". . . [this book] should be on the shelf of everyone interested in . . . longitudinal data analysis."—Journal of the American Statistical AssociationFeatures newly developed topics and applications of the analysis of longitudinal dataApplied Longitudinal Analysis, Second Edition presents modern methods for analyzing data from longitudinal studies and now features the ... Read more

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  • Bayesian Designs for Phase I-II Clinical Trials

    Series series Chapman & Hall/CRC Biostatistics Series
    Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources.Bayesian ... Read more

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  • Benefit-Risk Assessment Methods in Medical Product Development

    Bridging Qualitative and Quantitative Assessments

    Edited by Qi Jiang, Weili He ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Guides You on the Development and Implementation of B–R EvaluationsBenefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present ... Read more

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  • Practical Considerations for Adaptive Trial Design and Implementation

    Series series Mathematics and Statistics (R0)
    This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, ... Read more

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  • Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

    by Toshiro Tango ...
    Series series Chapman & Hall/CRC Biostatistics Series
    Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The author introduces a new repeated measures design called S:T design combined with mixed models as a ... Read more

    Was $72.99 USD Now $64.99 USD

  • Quick Guide to Good Clinical Practice

    How to Meet International Quality Standard in Clinical Research

    Series series Medicine (R0)
    This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard – Good Clinical Practice – provided by the International Conference on Harmonization (ICH).The work offers an updated perspective on the clinical research landscape within the context of the clinical trial regulatory frameworks in ... Read more

    $89.09 USD

  • Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

    Series series Chapman & Hall/CRC Handbooks of Modern Statistical Methods
    Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted ... Read more

    $110.99 USD