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1 - 12 de 23 resultados para “gerd folkers”
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  • Flugsommer

    de Gerd Folkers ...
    Nürnberg 1834: Zwei junge Männer kämpfen leidenschaftlich um die Zukunft der Luftfahrt. Der eine schwört auf den steuerbaren Ballon, der andere träumt vom Flugzeug. Was als Freundschaft begann, wird zum erbitterten Wettstreit. Medienrummel, Crowdfunding über Zeitungsanzeigen, üble Nachrede – kein Mittel ist ihnen zu schäbig, um den einstigen Freund zu vernichten. Während Carl Spitzweg das ... Leer más

    $29.99 USD

  • Animal Models for Human Cancer

    Discovery and Development of Novel Therapeutics

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results.Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the ... Leer más

    $129.00 USD

  • Fragment-based Drug Discovery

    Lessons and Outlook

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a comprehensive overview of current methods and applications of fragment-based discovery, as well as an outlook on where the field is headed ... Leer más

    $151.00 USD

  • Thermodynamics and Kinetics of Drug Binding

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects.Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and ... Leer más

    $151.00 USD

  • Protein Therapeutics

    de Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, ... Leer más

    $282.00 USD

  • Transporters as Drug Targets

    de Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Series series Methods & Principles in Medicinal Chemistry
    As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets.Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug ... Leer más

    $151.00 USD

  • Lead Generation

    Methods and Strategies

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series series Methods & Principles in Medicinal Chemistry
    In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation. This is the first book to combine both standard and innovative approaches in comparable breadth and depth, including several recent successful lead generation case studies published here for the ... Leer más

    $275.00 USD

  • Data Mining in Drug Discovery

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 57 - Methods & Principles in Medicinal Chemistry
    Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine. Clearly divided into four sections, the first part discusses the different data sources available, both commercial and non ... Leer más

    $141.00 USD

  • Microwaves in Organic and Medicinal Chemistry

    de C. Oliver Kappe, Alexander Stadler, Doris Dallinger, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 52 - Methods & Principles in Medicinal Chemistry
    Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed,almost doubling the amount of chemical information with an additional volume.As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation andequipment. The main part of the book then ... Leer más

    $170.00 USD

  • Medicinal Chemistry Approaches to Personalized Medicine

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 59 - Methods & Principles in Medicinal Chemistry
    Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues.Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities ... Leer más

    $126.00 USD

  • Phosphodiesterases and Their Inhibitors

    de Raimund Mannhold, Hugo Kubinyi, Gerd Folkers ...
    Series Libro 61 - Methods & Principles in Medicinal Chemistry
    Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug.Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, ... Leer más

    $142.00 USD

  • Natural Products in Medicinal Chemistry

    de Hugo Kubinyi, Gerd Folkers, Raimund Mannhold ...
    Series Libro 60 - Methods & Principles in Medicinal Chemistry
    The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters.Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new ... Leer más

    $146.00 USD