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1 - 12 de 12 resultados para “sten orrenius”
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  • Mitochondrial Signaling in Health and Disease

    Edición de Sten Orrenius, Lester Packer, Enrique Cadenas ...
    Series series Oxidative Stress and Disease
    Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic ... Leer más

    $280.00 USD

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  • Nutrition in Epigenetics

    Edición de Mihai D. Niculescu, Paul Haggarty ...
    The study of epigenetics, or how heritable changes in gene expression are regulated without modifying the coding DNA sequence, has become an increasingly important field of study in recent years. Rapid developments in our understanding of the way in which gene function is modulated by the environment has revolutionized the way we think about human development and health. Nutrition in Epigenetics ... Leer más

    $209.00 USD

  • Protein Misfolding Diseases

    Current and Emerging Principles and Therapies

    Edición de Marina Ramirez-Alvarado, Jeffery W. Kelly, Christopher M. Dobson ...
    Series Libro 14 - Wiley Series in Protein and Peptide Science
    An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific ... Leer más

    $218.00 USD

  • Handbook of Cell Signaling

    Edición de Ralph A. Bradshaw, Edward A. Dennis ...
    Series series Cell Biology
    Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular ... Leer más

    $481.99 USD

  • Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

    Edición de Yvonne Will, James A. Dykens ...
    Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.• Covers both basic science and applied technology / methods• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects• ... Leer más

    $334.00 USD

  • The Inhibitor Index

    A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

    de Daniel Purich ...
    Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a process of interest is functionally linked to a particular enzyme or receptor. From antibiotics to ... Leer más

    $325.00 USD

  • Medicinal Chemistry of Anticancer Drugs

    de Carmen Avendaño, J. Carlos Menéndez ...
    Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research ... Leer más

    $179.99 USD

  • Redox Regulation of Differentiation and De-differentiation

    Edición de Carsten Berndt, Christopher Lillig ...
    Series series Oxidative Stress and Disease
    Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including ... Leer más

    $88.99 USD

  • Mitochondria and Cancer

    Edición de Keshav Singh, Leslie Costello ...
    Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration ... Leer más

    $134.99 USD

  • Protein Chaperones and Protection from Neurodegenerative Diseases

    de Vladimir Uversky ...
    Series Libro 7 - Wiley Series in Protein and Peptide Science
    How protein chaperones protect cells from neurodegenerative diseasesIncluding contributions from leading experts, Protein Chaperones and Protection from Neurodegenerative Diseases provides an in-depth exploration of how protein chaperones are involved in shielding cells from toxic aggregated or misfolded protein states that cause ALS, Parkinson's, and related diseases.Examining how different ... Leer más

    $144.00 USD

  • The AH Receptor in Biology and Toxicology

    de Raimo Pohjanvirta ...
    This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this ... Leer más

    $158.00 USD

  • Cytochrome P450 2D6

    Structure, Function, Regulation and Polymorphism

    de Shufeng Zhou ...
    Cytochromes are proteinsthat catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, ... Leer más

    $70.99 USD