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  • The Dynamic Synapse

    Molecular Methods in Ionotropic Receptor Biology

    Series series Frontiers in Neuroscience
    Exploring the diverse tools and technologies used to study synaptic processes, The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology delineates techniques, methods, and conceptual advances for studying neurotransmitter receptors and other synaptic proteins. It describes a broad range of molecular, biochemica ... Leer más

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  • Parkinson's Disease

    Molecular and Therapeutic Insights From Model Systems

    Edición de Richard Nass, Serge Przedborski ...
    Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely ... Leer más

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  • Protein Misfolding Diseases

    Current and Emerging Principles and Therapies

    Series Libro 14 - Wiley Series in Protein and Peptide Science
    An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific ... Leer más

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  • Molecular Pharmacology

    From DNA to Drug Discovery

    This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. ... Leer más

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  • Epigenetic Regulation and Epigenomics

    Edición de Robert A. Meyers ...
    Series series Advances in Molecular Biology and Medicine
    Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused ... Leer más

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  • Biased Signaling in Physiology, Pharmacology and Therapeutics

    Edición de Brian J Arey ...
    Biased Signaling in Physiology, Pharmacology and Therapeutics is a unique and essential reference for the scientific community concerning how conformational-dependent activation is a common phenomenon across many classes of receptors or signaling molecules. It discusses the role of conformational dynamics in leading to signaling bias across different classes of receptors and signaling molecules. ... Leer más

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  • Epigenetics in Cancer

    de Wiley ...
    Series series Life Science Research Fundamentals
    Epigenetics is the study of heritable changes in gene expression or cellular phenotype, caused by mechanisms other than changes in the DNA sequence. Examples include DNA methylation and histone modification. These changes may remain through cell divisions and multiple generations. Epigenetic differences among individuals may account for some of the differences between monozygotic (identical) twins ... Leer más

    $29.00 USD

  • Behavioral Genetics of the Fly (Drosophila Melanogaster)

    Edición de Josh Dubnau ...
    Series series Cambridge Handbooks in Behavioral Genetics
    The common fruit fly - Drosophila melanogaster - has been the subject of genetics research since the early twentieth century. The complete genomic sequence of Drosophila was published in 2000 and it is still the model organism par excellence for the experimental study of biological phenomena and processes. It is also by far the best model for studying gene function in mammals, including humans. ... Leer más

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  • Protein Kinase CK2

    Series Libro 6 - The Wiley-IUBMB Series on Biochemistry and Molecular Biology
    Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its ... Leer más

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  • Handbook of Epigenetics

    The New Molecular and Medical Genetics

    Edición de Trygve O. Tollefsbol ...
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic ... Leer más

    $179.99 USD

  • Handbook of Epigenetics

    The New Molecular and Medical Genetics

    Edición de Trygve O. Tollefsbol ...
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related ... Leer más

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  • Cell Press Reviews: Core Concepts in Cell Biology

    Edición de Cell Press ...
    Series series Cell Press Reviews Series
    Written by leading cell biologists and curated by Cell Press editors, reviews in the Cell Press Reviews: Core Concepts in Cell Biology publication informs, inspires, and connects cell biologists at all stages in their careers with timely, comprehensive insight into the most recent exciting developments across cell biology and hot topics within core areas of the field including: - Signaling ... Leer más

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